翻訳と辞書 Words near each other ・ Rica ・ Ribosomal protein S19 ・ Ribosomal protein s6 ・ Ribosomal protein SA ・ Ribosomal rescue factor ・ Ribosomal RNA ・ Ribosomal S15 leader ・ Ribosomal s6 kinase ・ Ribosomal translocation ・ Ribosomal-protein-alanine N-acetyltransferase ・ Ribosomally synthesized and post-translationally modified peptides ・ Ribosome ・ Ribosome biogenesis ・ Ribosome biogenesis protein BRX1 homolog ・ Ribosome display ・ Ribosome profiling ・ Ribosome Recycling Factor ・ Ribosome shunting ・ Ribosome-inactivating protein ・ Ribosome-nascent chain complex ・ Ribosomopathy ・ Ribostamycin ・ Riboswitch ・ Ribosyldihydronicotinamide dehydrogenase (quinone) ・ Ribosylnicotinamide kinase ・ Ribosylpyrimidine nucleosidase ・ Ribot ・ Ribot (horse) ・ Ribot's Law ・ Ribota Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Ribosome profiling ： ウィキペディア英語版 Ribosome profiling Ribosome profiling, or Ribo-Seq, is a technique developed by Nick Ingolia and Jonathan Weissman that uses specialized messenger RNA (mRNA) sequencing to determine which mRNAs are being actively translated. It produces a “global snapshot” of all the ribosomes active in a cell at a particular moment, called as translatome. Consequently, this enables researchers to identify the location of translation start sites, their distribution, and the speed of the translating ribosomes. Ribosome profiling involves similar sequencing library preparation and data analysis to RNA-Seq, but unlike RNA-Seq, which sequences all of the mRNA of a given sequence present in a sample, ribosome profiling targets only mRNA sequences protected by the ribosome during the process of decoding by translation.〔 ==History== Ribosome profiling is based on the discovery that the mRNA within a ribosome can be isolated through the use of nucleases that degrade unprotected mRNA regions. This technique analyzes the regions of mRNAs being converted to protein, as well as the levels of translation of each region to provide insight into global gene expression. Prior to its development, efforts to measure translation in vivo included microarray analysis on the RNA isolated from polysomes, as well as translational profiling through the affinity purification of epitope tagged ribosomes. These are useful and complementary methods, but neither allows the sensitivity and positional information provided by ribosome profiling.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ribosome profiling」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.